Biological Mechanisms

Innovation Lab for Nutrition Legacy Report: 2010-2021

Publication Type

The Innovation Lab for Nutrition Legacy Report serves as the culmination of our work as a USAID-funded Feed the Future Innovation Lab over the past 11 years, from 2010-2021. The report highlights key achievements and lessons learned from the lab’s nutrition research and capacity building activities in Feed the Future focus countries including Bangladesh, Egypt, Ethiopia, Malawi, Mozambique, Nepal, Tanzania, Timor Leste, and Uganda.

Assessing the Relationship of Aflatoxin Exposure and Stunting in Children 6-59 Months of Age in 10 Districts of Nampula Province, Mozambique

Publication Type

The aim of this study was to enumerate the serum aflatoxin B1 (AFB1) in children 6-59 months of age, and estimate its association with linear growth in these children. To accomplish this aim, the team conducted a cross-sectional study that focused on understanding the extent and level of aflatoxin exposure as measured through presence in a serum sample from children. We also studied the association between serum aflatoxin and chronic malnutrition (stunting), accounting for other risk factors. The specific objectives of this study include: 1.

Avaliação da Relação entre a Exposição à Aflatoxina e a Desnutrição Crónica em crianças dos 6 aos 59 meses em 10 Distritos na Província de Nampula, Moçambique (POR)

Publication Type

O objectivo principal deste estudo foi avaliar os níveis de aflatoxina B1 (AFB1) sérica em crianças de 6 a 59 meses de idade e estimar a sua associação com o crescimento linear nessas crianças. Para atingir esse objectivo, a equipa conduziu um estudo transversal que se focou em compreender a extensão e o nível de exposição à aflatoxina, determinando a sua presença em amostras de soro de crianças. Também se estudou a associação entre aflatoxina sérica e desnutrição crónica, considerando outros fatores de risco. Os objectivos específicos deste estudo incluem: 1.

Markers of Environmental Enteric Dysfunction Are Associated with Poor Growth and Iron Status in Rural Ugandan Infants

Publication Type

Abstract

Background

Environmental enteric dysfunction (EED), characterized by altered intestinal permeability/inflammation, microbial translocation, and systemic inflammation (SI), may be a significant contributor to micronutrient deficiencies and poor growth in infants from low-resource settings.

Objective

We examined associations among EED, SI, growth, and iron status at 6 mo of age.

Methods